Discovery of potent aryl-substituted 3-[(3-methylpyridine-2-carbonyl) amino]-2,4-dimethyl-benzoic acid EP4 antagonists with improved pharmacokinetic profile

Autor: Blanco, Maria-Jesus, Vetman, Tatiana, Chandrasekhar, Srinivasan, Fisher, Matthew J., Harvey, Anita, Chambers, Mark, Lin, Chaohua, Mudra, Daniel, Oskins, Jennifer, Wang, Xu-Shan, Yu, Xiao-Peng, Warshawsky, Alan M.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 February 2016 26(3):931-935
Databáze: ScienceDirect