Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of cancers

Autor:	Barlaam, Bernard, Cosulich, Sabina, Delouvrié, Bénédicte, Ellston, Rebecca, Fitzek, Martina, Germain, Hervé, Green, Stephen, Hancox, Urs, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Lebraud, Honorine, Magnien, Françoise, Lamorlette, Maryannick, Le Griffon, Antoine, Morgentin, Rémy, Ouvry, Gilles, Page, Ken, Pasquet, Georges, Polanska, Urszula, Ruston, Linette, Saleh, Twana, Vautier, Michel, Ward, Lara
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 15 November 2015 25(22):5155-5162
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect