Identification of 1-{2-[4-chloro-1′-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4′-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y1 antagonist as an antiplatelet agent

Autor: Jeon, Yoon T., Yang, Wu, Qiao, Jennifer X., Li, Ling, Ruel, Rejean, Thibeault, Carl, Hiebert, Sheldon, Wang, Tammy C., Wang, Yufeng, Liu, Yajun, Clark, Charles G., Wong, Henry S., Zhu, Juliang, Wu, Dauh-Rurng, Sun, Dawn, Chen, Bang-Chi, Mathur, Arvind, Chacko, Silvi A., Malley, Mary, Chen, Xue-Qing, Shen, Hong, Huang, Christine S., Schumacher, William A., Bostwick, Jeffrey S., Stewart, Anne B., Price, Laura A., Hua, Ji, Li, Danshi, Levesque, Paul C., Seiffert, Dietmar A., Rehfuss, Robert, Wexler, Ruth R., Lam, Patrick Y.S.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 March 2014 24(5):1294-1298
Databáze: ScienceDirect
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