Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties

Autor: Xiao, Dong, Zhu, Xiaohong, Yu, Younong, Shao, Ning, Wu, Jie, McCormick, Kevin D., Dhondi, Pawan, Qin, Jun, Mazzola, Robert, Tang, Haiqun, Rao, Ashwin, Siliphaivanh, Phieng, Qiu, Hongchen, Yang, Xiaoxin, Rivelli, Maria, Garlisi, Charles G., Eckel, Steve, Mukhopadhyay, Gitali, Correll, Craig, Rindgen, Diane, Aslanian, Robert, Palani, Anandan
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 March 2014 24(6):1615-1620
Databáze: ScienceDirect
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