Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects

Autor: Sun, Shaoyi, Zhang, Zaihui, Raina, Vandna, Pokrovskaia, Natalia, Hou, Duanjie, Namdari, Rostam, Khakh, Kuldip, Ratkay, Leslie G., McLaren, David G., Mork, Monica, Fu, Jianmin, Ferreira, Suzie, Hubbard, Brian, Winther, Michael D., Dales, Natalie
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 January 2014 24(2):526-531
Databáze: ScienceDirect