Discovery of (S,E)-3-(2-fluorophenyl)-N-(1-(3-(pyridin-3-yloxy)phenyl)ethyl)-acrylamide as a potent and efficacious KCNQ2 (Kv7.2) opener for the treatment of neuropathic pain

Autor: Wu, Yong-Jin, Conway, Charles M., Sun, Li-Qiang, Machet, Frederic, Chen, Jie, Chen, Ping, He, Huan, Bourin, Clotilde, Calandra, Vincenzo, Polino, Joseph L., Davis, Carl D., Heman, Karen, Gribkoff, Valentin K., Boissard, Christopher G., Knox, Ronald J., Thompson, Mark W., Fitzpatrick, William, Weaver, David, Harden, David G., Natale, Joanne, Dworetzky, Steven I., Starrett, John E., Jr.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 November 2013 23(22):6188-6191
Databáze: ScienceDirect
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