Discovery and optimisation of 1-hydroxyimino-3,3-diphenylpropanes, a new class of orally active GPBAR1 (TGR5) agonists

Autor: Dehmlow, Henrietta, Alvarez Sánchez, Rubén, Bachmann, Stephan, Bissantz, Caterina, Bliss, Fritz, Conde-Knape, Karin, Graf, Martin, Martin, Rainer E., Obst Sander, Ulrike, Raab, Susanne, Richter, Hans G.F., Sewing, Sabine, Sprecher, Urs, Ullmer, Christoph, Mattei, Patrizio
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 August 2013 23(16):4627-4632
Databáze: ScienceDirect