Structure-based design, SAR analysis and antitumor activity of PI3K/mTOR dual inhibitors from 4-methylpyridopyrimidinone series

Autor: Cheng, Hengmiao, Hoffman, Jacqui E., Le, Phuong T., Pairish, Mason, Kania, Robert, Farrell, William, Bagrodia, Shubha, Yuan, Jing, Sun, Shaoxian, Zhang, Eric, Xiang, Cathy, Dalvie, Deepak, Rahavendran, Sadayappan V.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 May 2013 23(9):2787-2792
Databáze: ScienceDirect