Use of core modification in the discovery of CC214-2, an orally available, selective inhibitor of mTOR kinase

Autor: Mortensen, Deborah S., Sapienza, John, Lee, Branden G.S., Perrin-Ninkovic, Sophie M., Harris, Roy, Shevlin, Graziella, Parnes, Jason S., Whitefield, Brandon, Hickman, Matt, Khambatta, Gody, Bisonette, Rene R., Peng, Sophie, Gamez, Jim C., Leisten, Jim, Narla, Rama Krishna, Fultz, Kimberly E., Sankar, Sabita
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 March 2013 23(6):1588-1591
Databáze: ScienceDirect