Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux

Autor: Rzasa, Robert M., Hu, Essa, Rumfelt, Shannon, Chen, Ning, Andrews, Kristin L., Chmait, Samer, Falsey, James R., Zhong, Wenge, Jones, Adrie D., Porter, Amy, Louie, Steven W., Zhao, Xiaoning, Treanor, James J.S., Allen, Jennifer R.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 December 2012 22(24):7371-7375
Databáze: ScienceDirect
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