Pyrazolopyridine inhibitors of B-RafV600E. Part 3: An increase in aqueous solubility via the disruption of crystal packing

Autor: Wenglowsky, Steve, Moreno, David, Rudolph, Joachim, Ran, Yingqing, Ahrendt, Kateri A., Arrigo, Alisha, Colson, Ben, Gloor, Susan L., Hastings, Gregg
Zdroj: In Bioorganic & Medicinal Chemistry Letters 15 January 2012 22(2):912-915
Databáze: ScienceDirect