A three-step protocol for lead optimization: Quick identification of key conformational features and functional groups in the SAR studies of non-ATP competitive MK2 (MAPKAPK2) inhibitors

Autor: Huang, Xianhai, Zhu, Xiaohong, Chen, Xiao, Zhou, Wei, Xiao, Dong, Degrado, Sylvia, Aslanian, Robert, Fossetta, James, Lundell, Daniel, Tian, Fang, Trivedi, Prashant, Palani, Anandan
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 January 2012 22(1):65-70
Databáze: ScienceDirect