Discovery of novel 5-alkynyl-4-anilinopyrimidines as potent, orally active dual inhibitors of EGFR and Her-2 tyrosine kinases

Autor: Suzuki, Naoyuki, Shiota, Takeshi, Watanabe, Fumihiko, Haga, Norihiro, Murashi, Takami, Ohara, Takafumi, Matsuo, Kenji, Omori, Naoki, Yari, Hiroshi, Dohi, Keiji, Inoue, Makiko, Iguchi, Motofumi, Sentou, Jyunko, Wada, Tooru
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 January 2012 22(1):456-460
Databáze: ScienceDirect