Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014

Autor:	Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Wood, Douglas E., Wood, Kathleen M., Van Deusen, Jeffrey W., Zhang, Lei
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 2011 21(9):2637-2640
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect