Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors

Autor: Avvaru, Balendu Sankara, Wagner, Jason M., Maresca, Alfonso, Scozzafava, Andrea, Robbins, Arthur H., Supuran, Claudiu T., McKenna, Robert
Zdroj: In Bioorganic & Medicinal Chemistry Letters 1 August 2010 20(15):4376-4381
Databáze: ScienceDirect