Discovery of potent, selective, and orally bioavailable 3 H-spiro[isobenzofuran-1,4′-piperidine] based melanocortin subtype-4 receptor agonists

Autor:	Guo, Liangqin, Ye, Zhixiong, Liu, Jian, He, Shuwen, Bakshi, Raman K., Sebhat, Iyassu K., Dobbelaar, Peter H., Hong, Qingmei, Jian, Tianying, Dellureficio, James P., Tsou, Nancy N., Ball, Richard G., Weinberg, David H., MacNeil, Tanya, Tang, Rui, Tamvakopoulos, Constantin, Peng, Qianping, Chen, Howard Y., Chen, Airu S., Martin, William J., MacIntyre, D. Euan, Strack, Alison M., Fong, Tung M., Wyvratt, Matthew J., Nargund, Ravi P.
Zdroj:	In Bioorganic & Medicinal Chemistry Letters 2010 20(16):4895-4900
Databáze:	ScienceDirect
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect