Replacement of pyrazol-3-yl amine hinge binder with thiazol-2-yl amine: Discovery of potent and selective JAK2 inhibitors

Autor: Ioannidis, Stephanos, Lamb, Michelle L., Almeida, Lynsie, Guan, Huiping, Peng, Bo, Bebernitz, Geraldine, Bell, Kirsten, Alimzhanov, Marat, Zinda, Michael
Zdroj: In Bioorganic & Medicinal Chemistry Letters 2010 20(5):1669-1673
Databáze: ScienceDirect