Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Autor: Meyers, Marvin J., Pelc, Matthew, Kamtekar, Satwik, Day, Jacqueline, Poda, Gennadiy I., Hall, Molly K., Michener, Marshall L., Reitz, Beverly A., Mathis, Karl J., Pierce, Betsy S., Parikh, Mihir D., Mischke, Deborah A., Long, Scott A., Parlow, John J., Anderson, David R., Thorarensen, Atli
Zdroj: In Bioorganic & Medicinal Chemistry Letters 2010 20(5):1543-1547
Databáze: ScienceDirect