The discovery and optimisation of pyrido[2,3- d]pyrimidine-2,4-diamines as potent and selective inhibitors of mTOR kinase
| Autor: | Malagu, Karine, Duggan, Heather, Menear, Keith, Hummersone, Marc, Gomez, Sylvie, Bailey, Christine, Edwards, Peter, Drzewiecki, Jan, Leroux, Frédéric, Quesada, Mar Jimenez, Hermann, Gesine, Maine, Stephanie, Molyneaux, Carrie-Anne, Le Gall, Armelle, Pullen, James, Hickson, Ian, Smith, Lisa, Maguire, Sharon, Martin, Niall, Smith, Graeme, Pass, Martin |
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| Zdroj: | In Bioorganic & Medicinal Chemistry Letters 2009 19(20):5950-5953 |
| Databáze: | ScienceDirect |
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