Discovery of (3- endo)-3-(2-cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide as an efficacious inhaled muscarinic acetylcholine receptor antagonist for the treatment of COPD

Autor: Wan, Zehong, Laine, Dramane I., Yan, Hongxing, Zhu, Chongjie, Widdowson, Katherine L., Buckley, Peter T., Burman, Miriam, Foley, James J., Sarau, Henry M., Schmidt, Dulcie B., Webb, Edward F., Belmonte, Kristen E., Palovich, Michael
Zdroj: In Bioorganic & Medicinal Chemistry Letters 2009 19(16):4560-4562
Databáze: ScienceDirect