Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-( N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: Evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity
| Autor: | Chowdhury, Morshed Alam, Abdellatif, Khaled R.A., Dong, Ying, Rahman, Moshfiqur, Das, Dipankar, Suresh, Mavanur R., Knaus, Edward E. |
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| Zdroj: | In Bioorganic & Medicinal Chemistry Letters 2009 19(3):584-588 |
| Databáze: | ScienceDirect |
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