Optimization of a series of 4,6-bis-anilino-1 H-pyrrolo[2,3- d]pyrimidine inhibitors of IGF-1R: Elimination of an acid-mediated decomposition pathway
Autor: | Chamberlain, Stanley D., Redman, Anikó M., Patnaik, Samarjit, Brickhouse, Keith, Chew, Yen-Chiat, Deanda, Felix, Gerding, Roseanne, Lei, Huangshu, Moorthy, Ganesh, Patrick, Mark, Stevens, Kirk L., Wilson, Joseph W., Brad Shotwell, J. |
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Zdroj: | In Bioorganic & Medicinal Chemistry Letters 2009 19(2):373-377 |
Databáze: | ScienceDirect |
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