2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles—O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)
Autor: | Warmus, Joseph S., Flamme, Cathlin, Zhang, Lu Yan, Barrett, Stephen, Bridges, Alexander, Chen, Huifen, Gowan, Richard, Kaufman, Michael, Sebolt-Leopold, Judy, Leopold, Wilbur, Merriman, Ronald, Ohren, Jeffrey, Pavlovsky, Alexander, Przybranowski, Sally, Tecle, Haile, Valik, Heather, Whitehead, Christopher, Zhang, Erli |
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Zdroj: | In Bioorganic & Medicinal Chemistry Letters 1 December 2008 18(23):6171-6174 |
Databáze: | ScienceDirect |
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