Strategies toward improving the brain penetration of macrocyclic tertiary carbinamine BACE-1 inhibitors

Autor: Moore, Keith P., Zhu, Hong, Rajapakse, Hemaka A., McGaughey, Georgia B., Colussi, Dennis, Price, Eric A., Sankaranarayanan, Sethu, Simon, Adam J., Pudvah, Nicole T., Hochman, Jerome H., Allison, Timothy, Munshi, Sanjeev K., Graham, Samuel L., Vacca, Joseph P., Nantermet, Philippe G.
Zdroj: In Bioorganic & Medicinal Chemistry Letters 2007 17(21):5831-5835
Databáze: ScienceDirect