Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1 H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain
| Autor: | Kawai, Makoto, Ando, Kazuo, Matsumoto, Yukari, Sakurada, Isao, Hirota, Masako, Nakamura, Hiroshi, Ohta, Atsuko, Sudo, Masaki, Hattori, Kazunari, Takashima, Tadashi, Hizue, Masanori, Watanabe, Shuzo, Fujita, Isami, Mizutani, Mayumi, Kawamura, Mitsuhiro |
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| Zdroj: | In Bioorganic & Medicinal Chemistry Letters 2007 17(20):5558-5562 |
| Databáze: | ScienceDirect |
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