Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase

Autor: Thomas, Sheela A., Li, Tongmei, Woods, Keith W., Song, Xiaohong, Packard, Garrick, Fischer, John P., Diebold, Robert B., Liu, Xuesong, Shi, Yan, Klinghofer, Vered, Johnson, Eric F., Bouska, Jennifer J., Olson, Amanda, Guan, Ran, Magnone, Shayna R., Marsh, Kennan, Luo, Yan, Rosenberg, Saul H., Giranda, Vincent L., Li, Qun
Zdroj: In Bioorganic & Medicinal Chemistry Letters 2006 16(14):3740-3744
Databáze: ScienceDirect