Membrane 5α-pregnane-3,20-dione (5αP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5αP and down-regulated by the progesterone metabolites, 3α-dihydroprogesterone and 20α-dihydroprogesterone, with associated changes in cell proliferation and detachment

Autor: Pawlak, K.J., Zhang, G., Wiebe, J.P.
Zdroj: In Journal of Steroid Biochemistry and Molecular Biology 2005 97(3):278-288
Databáze: ScienceDirect