445 MEK inhibition enhances gemcitabine efficacy by increasing MDM2-mediated ubiquitination and degradation of RRM1

Autor: Vena, F., Li Causi, E., Hagemann, T., Hartley, J.A., Goodstal, S., Hochhauser, D.
Zdroj: In European Journal of Cancer November 2014 50 Supplement 6:146-146
Databáze: ScienceDirect