Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part II. A mechanistic PBPK model for IR formulation comparison, proton pump inhibitor drug interactions, and administration with acidic juices
| Autor: | Pepin, Xavier J.H., Moir, Andrea J., Mann, James C., Sanderson, Natalie J., Barker, Richard, Meehan, Elizabeth, Plumb, Allan P., Bailey, George R., Murphy, Dean S., Krejsa, Cecile M., Andrew, Marilee A., Ingallinera, Timothy G., Slatter, J. Greg |
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| Zdroj: | In European Journal of Pharmaceutics and Biopharmaceutics September 2019 142:435-448 |
| Databáze: | ScienceDirect |
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