Improvement in the water solubility of drugs with a solid dispersion system by spray drying and hot-melt extrusion with using the amphiphilic polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer and d-mannitol

Autor: Ogawa, Noriko, Hiramatsu, Tomoki, Suzuki, Ryohei, Okamoto, Ryohei, Shibagaki, Kohei, Fujita, Kosuke, Takahashi, Chisato, Kawashima, Yoshiaki, Yamamoto, Hiromitsu
Zdroj: In European Journal of Pharmaceutical Sciences 1 January 2018 111:205-214
Databáze: ScienceDirect