Characterization of stress degradation products of nintedanib by UPLC, UHPLC-Q-TOF/MS/MS and NMR: Evidence of a degradation product with a structure alert for mutagenicity

Autor: Dhiman, Vivek, Balhara, Ankit, Singh, Saranjit, Tiwari, Shristy, Gananadhamu, Samanthula, Talluri, M.V.N. Kumar
Zdroj: In Journal of Pharmaceutical and Biomedical Analysis 30 May 2021 199
Databáze: ScienceDirect