Discovery of novel fused-heterocycle-bearing diarypyrimidine derivatives as HIV-1 potent NNRTIs targeting tolerant region I for enhanced antiviral activity and resistance profile

Autor: Dai, Jiaojiao, Jiang, Xiangyi, Gao, Heng, Huang, Boshi, De Clercq, Erik, Pannecouque, Christophe, Du, Shaoqing, Liu, Xinyong, Zhan, Peng
Zdroj: In European Journal of Medicinal Chemistry 5 January 2025 281
Databáze: ScienceDirect