Discovery of 7-(1-methyl-1H-pyrazol-4-yl)-1,6-naphthyridine derivatives as potent inhibitors of rearranged during transfection (RET) and RET solvent-front mutants for overcoming selpercatinib resistance

Autor: Wu, Junbo, Mo, Hanxuan, An, Zhigang, Tang, Zishu, Deng, Xinyu, Zhou, Huifang, Gong, Yi, Zheng, Chenggong, Zhuo, Linsheng, Tan, Shuguang
Zdroj: In European Journal of Medicinal Chemistry 5 December 2024 279
Databáze: ScienceDirect