Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors

Autor: Ghosh, Arun K., Yadav, Monika, Iddum, Satyanarayana, Ghazi, Somayeh, Lendy, Emma K., Jayashankar, Uttara, Beechboard, Sydney N., Takamatsu, Yuki, Hattori, Shin-ichiro, Aamano, Masayuki, Higashi-Kuwata, Nobuyo, Mitsuya, Hiroaki, Mesecar, Andrew D.
Zdroj: In European Journal of Medicinal Chemistry 5 March 2024 267
Databáze: ScienceDirect