Rational design and optimization of novel 4-methyl quinazoline derivatives as PI3K/HDAC dual inhibitors with benzamide as zinc binding moiety for the treatment of acute myeloid leukemia

Autor: Zhang, Kehui, Huang, Rui, Ji, Ming, Lin, Songwen, Lai, Fangfang, Wu, Deyu, Tian, Hua, Bi, Jinhui, Peng, Shouguo, Hu, Jiaqi, Sheng, Li, Li, Yan, Chen, Xiaoguang, Xu, Heng
Zdroj: In European Journal of Medicinal Chemistry 15 January 2024 264
Databáze: ScienceDirect