Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation

Autor: Yu, Su, Zhang, Yan, Yang, Jie, Xu, Hongrui, Lan, Suke, Zhao, Binyan, Luo, Meng, Ma, Xinyu, Zhang, Hongjia, Wang, Shirui, Shen, Hui, Xu, Yong, Li, Rui
Zdroj: In European Journal of Medicinal Chemistry 5 January 2024 263
Databáze: ScienceDirect
Externí odkaz: