Discovery of a high potent PIM kinase inhibitor for acute myeloid leukemia based on N-pyridinyl amide scaffold by optimizing the fragments toward to Lys67 and Asp128/Glu171

Autor: Xiang, Ruiqing, Lu, Mingzhu, Wu, Tianze, Yang, Chengbin, Jia, Yu, Liu, Xiaofeng, Deng, Mingli, Ge, Yu, Xu, Jun, Cai, Tong, Ling, Yun, Zhou, Yaming
Zdroj: In European Journal of Medicinal Chemistry 5 September 2023 257
Databáze: ScienceDirect