HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues

Autor: Lockbaum, Gordon J., Rusere, Linah N., Henes, Mina, Kosovrasti, Klajdi, Rao, Desaboini Nageswara, Spielvogel, Ean, Lee, Sook-Kyung, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar
Zdroj: In European Journal of Medicinal Chemistry 5 September 2023 257
Databáze: ScienceDirect