Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis

Autor: Chen, Xuetao, Meng, Fanying, Zhang, Jingtian, Zhang, Zijian, Ye, Xuan, Zhang, Weikun, Tong, Yuanyuan, Ji, Xinrui, Xu, Rujun, Xu, Xiao-Li, You, Qi-Dong, Jiang, Zheng-Yu
Zdroj: In European Journal of Medicinal Chemistry 5 August 2022 238
Databáze: ScienceDirect