Design and synthesis of novel orally selective and type II pan-TRK inhibitors to overcome mutations by property-driven optimization

Autor: Li, Mu-Chun, Lin, Wen-Hsing, Wang, Pei-Chen, Su, Yu-Chieh, Chen, Pei-Yi, Fan, Chu-Min, Chen, Ching-Ping, Huang, Chen-Lung, Chiu, Chun-Hsien, Chang, Ling, Chen, Chiung-Tong, Yeh, Teng-Kuang, Hsieh, Hsing-Pang
Zdroj: In European Journal of Medicinal Chemistry 15 November 2021 224
Databáze: ScienceDirect