Targeting dihydrofolate reductase: Design, synthesis and biological evaluation of novel 6-substituted pyrrolo[2,3-d]pyrimidines as nonclassical antifolates and as potential antitumor agents

Autor: Gao, Tianfeng, Zhang, Congying, Shi, Xiaowei, Guo, Ran, Zhang, Kai, Gu, Jianmin, Li, Lin, Li, Shuolei, Zheng, Qianqian, Cui, Mengyu, Cui, Miao, Gao, Xingmei, Liu, Yi, Wang, Lei
Zdroj: In European Journal of Medicinal Chemistry 15 September 2019 178:329-340
Databáze: ScienceDirect