Design, synthesis and biological evaluation of novel substituted purine isosters as EGFR kinase inhibitors, with promising pharmacokinetic profile and in vivo efficacy

Autor: Gavriil, Efthymios-Spyridon, Doukatas, Aris, Karampelas, Theodoros, Myrianthopoulos, Vassilios, Dimitrakis, Spyridon, Mikros, Emmanuel, Marakos, Panagiotis, Tamvakopoulos, Constantin, Pouli, Nicole
Zdroj: In European Journal of Medicinal Chemistry 15 August 2019 176:393-409
Databáze: ScienceDirect