Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
| Autor: | Wang, Qiang, Liu, Feiyang, Qi, Shuang, Qi, Ziping, Yan, Xiao-E., Wang, Beilei, Wang, Aoli, Wang, Wei, Chen, Cheng, Liu, Xiaochuan, Jiang, Zongru, Hu, Zhenquan, Wang, Li, Wang, Wenchao, Ren, Tao, Zhang, Shanchun, Yun, Cai-Hong, Liu, Qingsong, Liu, Jing |
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| Zdroj: | In European Journal of Medicinal Chemistry 25 April 2018 150:366-384 |
| Databáze: | ScienceDirect |
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