54020 Potent and selective TYK2 degraders, devoid of JAK activity, potently and completely suppress IL12/23 and IFN-a signaling pathways.

Autor: Slavin, Anthony, Marx, Isaac, Wang, Amy, Byrne, Fergus, Wilkinson, Alex, Harsch, Andreas, Hu, Kan-Nian, Walther, Dirk, Karnik, Rahul, Mainolfi, Nello, Weiss, Matt
Zdroj: In Journal of the American Academy of Dermatology September 2024 91(3) Supplement:AB282-AB282
Databáze: ScienceDirect