Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings

Autor: Fan, Yuchen, Rigas, Diamanda, Kim, Lee Joon, Chang, Feng-Peng, Zang, Nanzhi, McKee, Kristina, Kemball, Christopher C., Yu, Zhixin, Winkler, Pascal, Su, Wan-Chih, Jessen, Pierce, Hura, Greg L., Chen, Tao, Koenig, Stefan G., Nagapudi, Karthik, Leung, Dennis, Yen, Chun-Wan
Zdroj: In Journal of Controlled Release September 2024 373:727-737
Databáze: ScienceDirect