The conformation-specific Hsp90 inhibition interferes with the oncogenic RAF kinase adaptation and triggers premature cellular senescence, hence, acts as a tumor suppressor mechanism
| Autor: | Kanugovi Vijayavittal, Abhijnya, Amere Subbarao, Sreedhar |
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| Zdroj: | In BBA - Molecular Cell Research March 2021 1868(3) |
| Databáze: | ScienceDirect |
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