Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators

Autor: Lotfy, Gehad, Abdel Aziz, Yasmine M., Said, Mohamed M., El Ashry, El Sayed H., El Tamany, El Sayed H., Abu-Serie, Marwa M., Teleb, Mohamed, Dömling, Alexander, Barakat, Assem
Zdroj: In Bioorganic Chemistry December 2021 117
Databáze: ScienceDirect