Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors
| Autor: | Chetter, Ben A., Kyriakis, Efthimios, Barr, Daniel, Karra, Aikaterini G., Katsidou, Elisabeth, Koulas, Symeon M., Skamnaki, Vassiliki T., Snape, Timothy J., Psarra, Anna-Maria G., Leonidas, Demetres D., Hayes, Joseph M. |
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| Zdroj: | In Bioorganic Chemistry September 2020 102 |
| Databáze: | ScienceDirect |
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