Improved Prediction of the Drug-Drug Interactions of Pemafibrate Caused by Cyclosporine A and Rifampicin via PBPK Modeling: Consideration of the Albumin-Mediated Hepatic Uptake of Pemafibrate and Inhibition Constants With Preincubation Against OATP1B

Autor: Park, Ji Eun, Shitara, Yoshihisa, Lee, Wooin, Morita, Shigemichi, Sahi, Jasminder, Toshimoto, Kota, Sugiyama, Yuichi
Zdroj: In Journal of Pharmaceutical Sciences January 2021 110(1):517-528
Databáze: ScienceDirect