Utilizing Physiologically Based Pharmacokinetic Modeling to Inform Formulation and Clinical Development for a Compound with pH-Dependent Solubility

Autor: Chung, John, Alvarez-Nunez, Fernando, Chow, Vincent, Daurio, Dominick, Davis, John, Dodds, Michael, Emery, Maurice, Litwiler, Kevin, Paccaly, Anne, Peng, Joanna, Rock, Brooke, Wienkers, Larry, Yang, Charles, Yu, Zhigang, Wahlstrom, Jan *
Zdroj: In Journal of Pharmaceutical Sciences April 2015 104(4):1522-1532
Databáze: ScienceDirect